Rem
I have a 43 Win in hornet. Im shooting the lyman225438gc bullet without worring about wearing out the barrel or overstressing the action. I would think the 22mag would be harder on the Martini than the hornet. I have a cadet with a short heavy barrel chambered in 222r that is very acurate with the match bullets Will try the cast sometime this summer. 222 probably a better choice than the hornetr.
One summer I killed more groundhogs with a #1 ruger tropical 458mag and 500gr. gcrn under 150yds than my varmint rifles. That was a very acurate rifle if you could handle the recoil.