Looks like they are made for the U.S. market as they are not like the Hull Cartridge Company stuff sold here. I think they copied the same warning as on U.S. boxes about damascus barrels. I've just looked at a similar box I have and the same information is on with the exception of the damascus warning. I would say that if you are using them in a British damascus barrelled gun that is in proof for 2 1/2" nitro stuff then they will be o.k. If in a U.S. damascus unproved gun they I would check with a well qualified gunsmith. Lagopus.....