Gentlemen, my very non-original comment is....
It's the bullet that does the work. Not the cartridge, not the kinetic energy, but the bullet.
Handloading resources for that 'anemic' cartridge on the interweb indicate that good hunting bullets that will properly upset and expand are available....
Anythings possible, but.... That .357 you referred to probably had a modern jacketed bullet expending its energy in the deer. My preference would be to only have lead ride through that bore. Just for grins, whatever pushed it along, the bullet is still pretty anemic. I'd vote for no expansion and see if it could get a little deeper into the game. The fellow that paid to have that rig made up, probably had a massive estate with game keepers and might have shot a deer or two with his tiger rifle among others.
