nitros all have 2 3/4" chambers...
loads you suggest would be fine for limited shooting...
No, they dont ed.
The 16s got 2 3/4 chambers around 1937. In the 1920s, the 12s and 20s were short chamber guns. Researcher will be along to give us the exact dates.
That said, Nitros were designed to put up with the heavier loads that were being developed and sold around this time. Yes, they are old guns, but, the loads you are suggesting are not from the magnum section at a mart somewhere.
There are folk who use 2 3/4 inch loads in shorter chamber guns, which, from all reports is doable if the loads are within the same spec, pressure wise as the loads the gun is designed for. I have been running 2 3/4 guns.
Good luck with your guns. I have a 1937 vintage 16, and it is a great gun for hunting.
Best,
Ted