That is as they say the million dollar question .
And the answer is yes, or , no .

It will depend on so many factors , type of gun , type of lever work , condition of gun ,etc.

O/U's with low bites such as Browning's and Winchester's , can come open when the bites are worn even with good lever springs .

SxS's with barrel extension's , cross bolts for example are less likely to providing they do not solely rely on the extension for bolting.