I still hope to find a decent Remington M-514 Routeledge to use rat shot cartridges in. We are overrun with carpenter bees that bore 1/2" holes and create tunnels in the rafters and joists of our wooden equipment sheds and barns. We are gradually replacing the sheds with all steel ones but I could still burn lots of .22 shot shells wing shooting those bees.
I remember well the first time I shot a poisonous snake with a "snake shot" cartridge in .22 magnum, the CCI ones with the blue frangible plastic nose cover for the shot. I was amazed to see that the snake absolutely did not move, not a flinch when the pellets struck. The load totally paralyzed the snake and I soon saw tiny droplets of blood oozing out of each shot hole. I dunno if that is 100% typical of how they react to the shot load but that's how I've seen them react. They are very good loads to carry in a revolver in snake country.