Well,I try not to shoot them in the meat with anything, Broadside on through the ribs, you will not ruin any meat with any calibre. Personally I do not have any small bore magnums as I have no use for them. I have a Mannlicher Schoenaur in 6.5MS, a 338-06, a 9.3x62 and a Russian single shot take-down in 308 Win which shoots really well for a $300 dollar gun, new. If I was allowed to keep only one rifle it would be the 338-06, an eminently sensible cartridge.
Mike