My Remington 541 with CCI Quiet LR length will hold a red squirrel brain size group out to 25 yards. That is the maximum range required. These will also penetrate a half-inch piece of plywood at that range and are as titled, quiet.
While it has a terrible trigger, I will offer that Aguilla 60 grain subsonics will cycle in a Ruger 10-22, but with the trigger, as it is I haven't figured out a purpose.
Just to maintain my status here on the board I'll mention too that red squirrels are good eating and much easier to skin than greys.
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